Description |
Explores the interactions of cells with their surroundings at a molecular and cell biological level. It begins with an introduction to a number of basic signal transduction pathways, a characterization of their respective receptors and the molecular pathways that communicate between the cell surface and the nucleus. Discusses how signaling establishes axes of cell polarity and migratory pathways by producing changes in the cytoskeleton, and how cells interact with extracellular matrix molecules. Addresses the cell's response to nutritional cues and other extracellular signals that influence cell growth, cell division and cell physiology. |