Course Id |
4144 |
Dept and Number |
CHM
448
|
Dept and Number |
MOL
448
|
Area |
|
Title |
Chemistry, Structure, and Structure-Function Relations of Nucleic Acids |
Description |
The chemistry and structure of mononucleotides, oligonucleotides, and polynucleotides and their helical complexes are presented as a basis for understanding and predicting the structures and structure-function relations of naturally occurring DNAs and RNAs. Functions to be considered include fidelity of DNA replication, and transcription, mutagenic mechanisms, molecular evolution, the roles of telomeres, and of recently discovered small RNAs, and nature and organization of the genetic code. |
Prerequisites |
General chemistry and one semester of organic chemistry. Open to juniors, seniors, graduate students in Molecular Biology, Chemistry, EEB, Physics and Chemical & Bioengineering. Others by permission of the instructor. |
Professor |
Jacques R. Fresco |